ANTIGENIC ANALYSIS OF FELINE AND BOVINE CHLAMYDIA-PSITTACI WITH MONOCLONAL-ANTIBODIES

被引：10

作者：

MATSUNO, H ^{[1
]}

FUKUSHI, H ^{[1
]}

YAMAGUCHI, T ^{[1
]}

HIRAI, K ^{[1
]}

机构：

[1] GIFU UNIV, FAC AGR, DEPT VET MICROBIOL, YANAGIDO 1-1, GIFU 50111, JAPAN

来源：

JOURNAL OF VETERINARY MEDICAL SCIENCE | 1991年 / 53卷 / 02期

关键词：

ANTIGENIC ANALYSIS; CHLAMYDIA-PSITTACI; MONOCLONAL ANTIBODY;

D O I：

10.1292/jvms.53.173

中图分类号：

S85 [动物医学（兽医学）];

学科分类号：

0906 ;

摘要：

Monoclonal antibodies were established for antigenic analysis of feline and bovine Chlamydia psittaci. The monoclonal antibodies recognized lipoplysaccharide (LPS), 56-64, 84 or 86 kDa antigens. At least 5 antibody-binding sites were detected on LPS with the monoclonal antibodies. The 56-64 kDa antigen was suggested to have both polypeptide and carbohydrate antibody binding sites. Immunoblotting analysis of cat and cattle sera indicated that the 56-64 kDa antigen is an important antigen in host immune response. The monoclonal antibodies are extremely useful tools to analyse the structure and function of chlamydial antigens.

引用

页码：173 / 179

页数：7

共 25 条

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