ALTERED CATALYTIC ACTIVITY OF AND DNA CLEAVAGE BY DNA TOPOISOMERASE II FROM HUMAN-LEUKEMIC CELLS SELECTED FOR RESISTANCE TO VM-26

被引：263

作者：

DANKS, MK ^{[1
]}

SCHMIDT, CA ^{[1
]}

CIRTAIN, MC ^{[1
]}

SUTTLE, DP ^{[1
]}

BECK, WT ^{[1
]}

机构：

[1] ST JUDE CHILDRENS RES HOSP,DEPT BIOCHEM & CLIN PHARMACOL,MEMPHIS,TN 38101

来源：

BIOCHEMISTRY | 1988年 / 27卷 / 24期

关键词：

D O I：

10.1021/bi00424a026

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

引用

页码：8861 / 8869

页数：9

共 46 条

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[9] THE INTERACTION BETWEEN NUCLEAR TOPOISOMERASE-II ACTIVITY FROM HUMAN-LEUKEMIA CELLS, EXOGENOUS DNA, AND 4'-(9-ACRIDINYLAMINO) METHANESULFON-M-ANISIDIDE (M-AMSA) OR 4-(4,6-0-ETHYLIDENE-BETA-D-GLUCOPYRANOSIDE) (VP-16) INDICATES THE SENSITIVITY OF THE CELLS TO THE DRUGS [J].

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[10] RECONSTITUTION OF INTERCALATOR-INDUCED DNA SCISSION BY AN ACTIVE COMPONENT FROM NUCLEAR EXTRACTS [J].

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