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SOMATOSTATIN INHIBITS RELEASE OF THYROTROPIN RELEASING FACTOR FROM ORGAN-CULTURES OF RAT HYPOTHALAMUS

被引：97
作者：
HIROOKA, Y
HOLLANDER, CS
SUZUKI, S
FERDINAND, P
JUAN, SI
机构：
来源：
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA | 1978年 / 75卷 / 09期
关键词：
D O I：
10.1073/pnas.75.9.4509
中图分类号：
O [数理科学和化学]; P [天文学、地球科学]; Q [生物科学]; N [自然科学总论];
学科分类号：
07 ; 0710 ; 09 ;
摘要：
Somatostatin in concentrations of 10-6 to 10-8 M inhibited basal release of thyrotoprin releasing factor in organ culture of rat hypothalamus. Norepinephrine in doses of 10-4-10-6 M induced released of thyrotropin releasing factor which increased progressively with time and was temperature and dose dependent. This enhanced thyrotropin-releasing-factor release was inhibited by somatostatin at 10-6-10-8 M.
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页码：4509 / 4513
页数：5
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