DETERMINATION OF MORPHINE IN POPPY STRAW BY HIGH-PERFORMANCE LIQUID-CHROMATOGRAPHY

被引：7

作者：

WU, CY

MICHAILIDIS, MS

WITTICK, JJ

机构：

[1] Merck Chemical Manu facturing Division, Merck and Co., Inc., Rahway

来源：

ANALYTICA CHIMICA ACTA | 1979年 / 108卷 / JUL期

关键词：

D O I：

10.1016/S0003-2670(01)93060-0

中图分类号：

O65 [分析化学];

学科分类号：

070302 ; 081704 ;

摘要：

A simple high-performance liquid Chromatographie method for determining morphine in poppy straw is reported. The sample (ca. 2g) is ground and extracted with 0.02 M HCl; after suitable treatment, the morphine is extracted into chloroform-propan-2-ol (3:1), the acidified extract is evaporated, the residue is dissolved in dilute acid, and after further extraction, 100-μl aliquots are injected into the Chromatograph. The method is specific and gives a precision of ±2% relative. © 1979.

引用

页码：233 / 239

页数：7

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