CGS-19755 IS A POTENT AND COMPETITIVE ANTAGONIST AT NMDA-TYPE RECEPTORS

被引：60

作者：

LEHMANN, J

CHAPMAN, AG

MELDRUM, BS

HUTCHISON, A

TSAI, C

WOOD, PL

机构：

[1] CIBA GEIGY CORP,DIV PHARMACEUT,DEPT RES,SUMMIT,NJ 07901

[2] INST PSYCHIAT,DEPT NEUROL,LONDON SE5 8AF,ENGLAND

来源：

EUROPEAN JOURNAL OF PHARMACOLOGY | 1988年 / 154卷 / 01期

关键词：

D O I：

10.1016/0014-2999(88)90368-8

中图分类号：

R9 [药学];

学科分类号：

1007 ;

摘要：

引用

页码：89 / 93

页数：5

共 9 条

[1]

BOAST CA, IN PRESS BRAIN RES

[2] ANTICONVULSANT ACTION AND BIOCHEMICAL EFFECTS IN DBA 2 MICE OF CPP (3-((+/-)-2-CARBOXYPIPERAZIN-4-YL)-PROPYL-1-PHOSPHONATE), A NOVEL N-METHYL-D-ASPARTATE ANTAGONIST [J].

CHAPMAN, AG ;

MELDRUM, BS ;

NANJI, N ;

WATKINS, JC .

EUROPEAN JOURNAL OF PHARMACOLOGY, 1987, 139 (01) :91-96

[3] ANTICONVULSANT ACTION OF EXCITATORY AMINO-ACID ANTAGONISTS [J].

CROUCHER, MJ ;

COLLINS, JF ;

MELDRUM, BS .

SCIENCE, 1982, 216 (4548) :899-901

[4] 2-AMINO-5-PHOSPHONOVALERATE(2APV), A POTENT AND SELECTIVE ANTAGONIST OF AMINO ACID-INDUCED AND SYNAPTIC EXCITATION [J].

DAVIES, J ;

FRANCIS, AA ;

JONES, AW ;

WATKINS, JC .

NEUROSCIENCE LETTERS, 1981, 21 (01) :77-81

[5] ACTION OF 3-((+/-2-CARBOXYPIPERAZIN-4-YL)-PROPYL-1-PHOSPHONIC ACID (CPP) - A NEW AND HIGHLY POTENT ANTAGONIST OF N-METHYL-D-ASPARTATE RECEPTORS IN THE HIPPOCAMPUS [J].

HARRIS, EW ;

GANONG, AH ;

MONAGHAN, DT ;

WATKINS, JC ;

COTMAN, CW .

BRAIN RESEARCH, 1986, 382 (01) :174-177

[6]

LEHMANN J, 1987, J PHARMACOL EXP THER, V240, P737

[7] CHARACTERIZATION OF THE EXCITATORY AMINO-ACID RECEPTOR-MEDIATED RELEASE OF [H-3] ACETYLCHOLINE FROM RAT STRIATAL SLICES [J].

LEHMANN, J ;

SCATTON, B .

BRAIN RESEARCH, 1982, 252 (01) :77-89

[8] EARLY AND LATE MECHANISMS OF INCREASED VASCULAR-PERMEABILITY FOLLOWING EXPERIMENTAL CEREBRAL INFARCTION [J].

PETITO, CK .

JOURNAL OF NEUROPATHOLOGY AND EXPERIMENTAL NEUROLOGY, 1979, 38 (03) :222-234

[9] ANTAGONISTS OF EXCITATORY AMINO-ACIDS AND CYCLIC GUANOSINE-MONOPHOSPHATE IN CEREBELLUM [J].

WOOD, PL ;

RICHARD, JW ;

PILAPIL, C ;

NAIR, NPV .

NEUROPHARMACOLOGY, 1982, 21 (12) :1235-1238

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