IMMUNOLOGICAL EFFECTS OF TOLUENE DIISOCYANATE EXPOSURE ON PAINTERS

被引：14

作者：

HUANG, J ^{[1
]}

WANG, X ^{[1
]}

CHEN, B ^{[1
]}

UEDA, A ^{[1
]}

AOYAMA, K ^{[1
]}

MATSUSHITA, T ^{[1
]}

机构：

[1] HUNAN MED UNIV,DEPT TOXICOL,CHANGSHA,PEOPLES R CHINA

来源：

ARCHIVES OF ENVIRONMENTAL CONTAMINATION AND TOXICOLOGY | 1991年 / 21卷 / 04期

关键词：

D O I：

10.1007/BF01183884

中图分类号：

X [环境科学、安全科学];

学科分类号：

08 ; 0830 ;

摘要：

Among the painters handling polyurethane varnish in two furniture manufacturing factories with high toluene diisocyanate (TDI) exposure (0.79 mg/m3 and 0.31 mg/m3), 26.3% and 15% subjects, respectively displayed asthmatic symptoms, lung function loss, and an increment in mast cell degranulation percentage specific to TDI. Some cases of TDI-linked contact dermatitis were also found among them, being elucidated by positive patch testing to TDI. However, the previous abnormalities could not be verified among the painters from another factory with TDI concentration below the TLV of it (0.11 mg/m3). It was concluded that both pulmonary hypersensitivity and contact sensitization to TDI had occurred in some of the painters included in this study, and that the immunologic effects of TDI was concentration dependent.

引用

页码：607 / 611

页数：5

共 22 条

[1] DETECTION OF IMMUNOLOGICALLY SENSITIZED ISOCYANATE WORKERS BY RAST AND INTRACUTANEOUS SKIN-TESTS [J].