EXPRESSION AND LOCALIZATION OF OXYTOCIN RECEPTOR GENE IN HUMAN UTERINE ENDOMETRIUM IN RELATION TO THE MENSTRUAL-CYCLE

被引：72

作者：

TAKEMURA, M

NOMURA, S

KIMURA, T

INOUE, T

ONOUE, H

AZUMA, C

SAJI, F

KITAMURA, Y

TANIZAWA, O

机构：

[1] OSAKA UNIV, SCH MED, DEPT OBSTET & GYNECOL, 2-2 YAMADAOKA, SUITA, OSAKA 565, JAPAN

[2] OSAKA UNIV, SCH MED, DEPT PATHOL, SUITA, OSAKA 565, JAPAN

来源：

ENDOCRINOLOGY | 1993年 / 132卷 / 04期

关键词：

D O I：

10.1210/en.132.4.1830

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

The expression of oxytocin receptor mRNA in the human uterus was investigated by polymerase chain reaction after mRNA reverse transcription; in addition, the mRNA was localized by means of in situ hybridization histochemistry. Strong positive signals were observed in myometrial cells at parturition. In nonpregnant human uterine endometrium, oxytocin receptor mRNA was expressed in glandular epithelial cells, but was not observed in stromal cells. The signal in the epithelial cells was stronger at the time of ovulation than during any other phase. The sequential changes in oxytocin receptor mRNA expression in nonpregnant endometrium suggest some alternative biological function of oxytocin in endometrium during the menstrual cycle.

引用

页码：1830 / 1835

页数：6

共 21 条

[1]

ANDERSON LL, 1973, HDB PHYSL ENDOCRINOL, P69

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