FRACTIONATION OF VIPERA RUSSELLI VENOM BY GEL FILTRATION .2. COMPARATIVE STUDY OF YELLOW AND WHITE VENOMS OF VIPERA RUSSELLI WITH SPECIAL REFERENCE TO LOCAL NECROTIZING AND LETHAL ACTIONS

被引：16

作者：

DIMITROV, GD

KANKONKAR, RC

机构：

[1] Department of Immunology, Haffkine Institute, Bombay

来源：

TOXICON | 1968年 / 5卷 / 04期

关键词：

D O I：

10.1016/0041-0101(68)90120-7

中图分类号：

R9 [药学];

学科分类号：

1007 ;

摘要：

A comparative study of white and yellow venoms of Vipera russelli was carried out by gel filtration and starch gel electrophoresis. It was found that proteolytic activity in the white venom was extremely low, while l-amino acid oxidase and phospholipase A activities were present in lesser amounts. Some substantial differences in the gel filtration elution diagrams of both venoms were observed. In both venoms there was an unidentified fluorescing substance, which probably performs the function of a co-factor to the toxic component. Some data supporting this suggestion are present. By gel filtration and starch gel electrophoresis, the lethal fraction was partially purified. © 1968.

引用

页码：283 / +

页数：1