BICYCLIC PYRAZOLINES, POTENTIAL CENTRAL NERVOUS-SYSTEM DEPRESSANTS AND ANTI-INFLAMMATORY AGENTS

被引：50

作者：

KRAPCHO, J

TURK, CF

机构：

[1] The Squibb Institute for Medical Research, New Jersey

来源：

JOURNAL OF MEDICINAL CHEMISTRY | 1979年 / 22卷 / 02期

关键词：

D O I：

10.1021/jm00188a018

中图分类号：

R914 [药物化学];

学科分类号：

100701 ;

摘要：

The synthesis and CNS activity of a series of 34 substituted bicyclic pyrazolines are described. Ten of these compounds were also screened for antiinflammatory activity. One of the compounds (15) exhibited significant antiinflammatory activity in the carrageenan-induced edema test. © 1979, American Chemical Society. All rights reserved.

引用

页码：207 / 210

页数：4

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[2]

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[3]

JARBOE H, 1967, CHEM HETEROCYCL COMP, V22, P177

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[5]

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[6]

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