UNPRECEDENTED REARRANGEMENT OF 5-BENZOYL SUBSTITUTED BICYCLIC ISOXAZOLIDINES TO DEHYDRO PYRROLIZIDIN-2-ONES AND INDOLIZIDIN-2-ONES

被引：4

作者：

CORDERO, FM

BRANDI, A

DESARLO, F

VITI, G

机构：

[1] UNIV FLORENCE,DIPARTIMENTO CHIM ORGAN U SCHIFF,I-50121 FLORENCE,ITALY

[2] UNIV FLORENCE,CNR,CTR COMPOSTI ETEROCICLICI,I-50121 FLORENCE,ITALY

[3] MENARINI IND FARMACEUT RINUITE SRL,I-50131 FLORENCE,ITALY

来源：

JOURNAL OF THE CHEMICAL SOCIETY-CHEMICAL COMMUNICATIONS | 1994年 / 09期

关键词：

D O I：

10.1039/c39940001047

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

5-Benzoyl substituted isoxazolidines 3, obtained by 1,3-dipolar cycloadditions of pyrroline N-oxide and tetrahydropyridine N-oxide to phenyl vinyl ketone, undergo a rearrangement to dehydro 3-phenyl-pyrrolizidin-2-one and 3-phenylindolizidin-2-one catalysed by Al2O3; the rearrangement products undergo a Michael addition to a second molecule of phenyl vinyl ketone.

引用

页码：1047 / 1048

页数：2

共 26 条

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