VISUAL IMPAIRMENT IN PARKINSONS-DISEASE - DEFICITS IN ORIENTATION AND MOTION DISCRIMINATION

被引:46
作者
TRICK, GL
KASKIE, B
STEINMAN, SB
机构
[1] School of Optometry and Department of Ophthalmology, University of Montreal, Montreal, QC
[2] Department of Psychology, Washington University, St. Louis, MO
[3] Department of Ophthalmology, Washington University, St. Louis, MO
关键词
VISION; ORIENTATION DISCRIMINATION; MOTION DISCRIMINATION; VISUAL PSYCHOPHYSICS;
D O I
10.1097/00006324-199404000-00002
中图分类号
R77 [眼科学];
学科分类号
100212 ;
摘要
Purpose. In order to obtain a better understanding of the pathophysiology of visual impairment in Parkinson's disease (PD), orientation and motion discrimination were investigated in PD patients. Methods. Orientation and motion discrimination thresholds were assessed psychophysically in PD patients with normal cognition (N = 11) and compared to results for age-matched controls (N = 22). Results. PD patients exhibited a significant deficit in orientation discrimination for horizontal but not for vertical gratings. Also, motion discrimination thresholds were elevated significantly in PD patients. No significant correlations were found between motion and orientation discrimination thresholds. Conclusions. Our results indicate that PD patients exhibit significant visual dysfunction in the absence of cognitive impairment supporting the contention that neural dysfunction in PD is more generalized than previously realized. The results provide further evidence of an orientation selective visual deficit in PD and show that the ability to discriminate global motion is also attenuated in PD.
引用
收藏
页码:242 / 245
页数:4
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