EVALUATION OF TABLETED MICROSPHERES OF DIPYRIDAMOLE

被引：5

作者：

GURSOY, A ^{[1
]}

TURKOGLU, M ^{[1
]}

SENYUCEL, B ^{[1
]}

KALKAN, K ^{[1
]}

OKAR, I ^{[1
]}

机构：

[1] UNIV MARMARA,FAC MED,DEPT HISTOL & EMBRYOL,ISTANBUL,TURKEY

来源：

DRUG DEVELOPMENT AND INDUSTRIAL PHARMACY | 1995年 / 21卷 / 04期

关键词：

D O I：

10.3109/03639049509026639

中图分类号：

R914 [药物化学];

学科分类号：

100701 ;

摘要：

Microspheres of dipyridamole were prepared by solvent evaporation methods. The effect of additives Avicel PH 101, and beta cyclodextrin on the release rate of tableted microspheres were studied. Incorporating Avicel or beta cyclodextrin increased the dipyridamole release rates in tableted microspheres. Beta cyclodextrin was found to be a good additive for microsphere tablets to increase the drug release rates without causing disintegration.

引用

页码：503 / 507

页数：5