PHARMACOKINETICS OF ANTIBIOTICS IN THE LOWER RESPIRATORY-TRACT - LIMITED PRACTICAL VALUE OF THIS INFORMATION

被引:6
作者
BERGOGNEBEREZIN, E
机构
来源
MEDECINE ET MALADIES INFECTIEUSES | 1992年 / 22卷
关键词
CONCENTRATIONS; ANTIBIOTICS; TISSUE DISTRIBUTION; ANTIBIOTIC ASSAY; CLINICAL SIGNIFICANCE;
D O I
10.1016/S0399-077X(05)81459-3
中图分类号
R51 [传染病];
学科分类号
100401 ;
摘要
The antibiotic concentrations as measured in tissues and fluids of the lower respiratory tract are reported in this study ; several models have been used and new protocols recently proposed have provided more precise and reliable results. Various theoretical aspects and experimental factors of variation are discussed as well as the clinical significance of tissue pharmacokinetics in the respiratory tree.
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页码:103 / 113
页数:11
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