OPTIMIZATION OF PHARMACEUTICAL FORMULATIONS BASED ON RESPONSE-SURFACE EXPERIMENTAL-DESIGNS

被引：26

作者：

GONZALEZ, AG

机构：

[1] Department of Analytical Chemistry University of Seville

来源：

INTERNATIONAL JOURNAL OF PHARMACEUTICS | 1993年 / 97卷 / 1-3期

关键词：

PHARMACEUTICAL FORMULATION; OPTIMIZATION; FACTORIAL DESIGN; SIMPLEX LATTICE DESIGN; RESPONSE SURFACE MODEL BUILDING;

D O I：

10.1016/0378-5173(93)90135-3

中图分类号：

R9 [药学];

学科分类号：

1007 ;

摘要：

Optimization techniques for pharmaceutical formulations based on second order orthogonal or rotatable designs as well as simplex lattice designs have been revisited. A digest of the procedures for optimizing pharmaceutical formulations is given.

引用

页码：149 / 159

页数：11

共 17 条

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