ALKALI-METAL FLUORIDES AS EFFICIENT FLUORINATING AGENTS - ENANTIOCONTROLLED SYNTHESIS OF 2-FLUOROALKYL CARBOXYLATES AND 1-FLUOROALKYL BENZENES

被引：14

作者：

FRITZLANGHALS, E

机构：

[1] Consortium für Elektrochemische Industrie GmbH, Central Research Company, Wacker-Chemie GmbH, D-81379 München

来源：

TETRAHEDRON-ASYMMETRY | 1994年 / 5卷 / 06期

关键词：

D O I：

10.1016/0957-4166(94)80048-0

中图分类号：

O61 [无机化学];

学科分类号：

070301 ; 081704 ;

摘要：

Potassium fluoride and cesium fluoride in formamide, N-methylformamide, or acetamide are efficient fluorinating agents. They can be used for the enantiocontrolled synthesis of 2-fluorocarboxylic acids 1a and 1-fluoroalkyl benzenes 1b from the corresponding sulfonates which are easily available in high enantiomeric purity. The scope and limitation of the synthetic method is discussed.

引用

页码：981 / 986

页数：6

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