SPIRONOLACTONE AND TESTICULAR CYTOCHROME-P-450 - DECREASED TESTOSTERONE FORMATION IN SEVERAL SPECIES AND CHANGES IN HEPATIC DRUG-METABOLISM

被引：130

作者：

MENARD, RH ^{[1
]}

STRIPP, B ^{[1
]}

GILLETTE, JR ^{[1
]}

机构：

[1] NHLI,LAB CHEM PHARMACOL,BETHESDA,MD 20014

来源：

ENDOCRINOLOGY | 1974年 / 94卷 / 06期

关键词：

D O I：

10.1210/endo-94-6-1628

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

引用

页码：1628 / 1636

页数：9

共 22 条

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[3]

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[5] INVESTIGATION OF EFFECTS OF METHYLTESTOSTERONE, CORTISONE AND SPIRONOLACTONE ON HEPATIC MICROSOMAL MIXED-FUNCTION OXIDASE SYSTEM IN MALE AND FEMALE RATS [J].

HAMRICK, ME ;

ZAMPAGLIONE, NG ;

STRIPP, B ;

GILLETTE, JR .

BIOCHEMICAL PHARMACOLOGY, 1973, 22 (03) :293-310

[6]

MENARD R H, 1972, Federation Proceedings, V31, P485

[7] STIMULATION OF LEVELS OF CYTOCHROME-P-450 AND 17-ALPHA-HYDROXYLASE IN CHICK TESTIS MICROSOMES BY PITUITARY HORMONES [J].

MENARD, RH ;

PURVIS, JL .

ENDOCRINOLOGY, 1972, 91 (06) :1506-1512

[8] STUDIES OF CYTOCHROME-P-450 IN TESTIS MICROSOMES [J].

MENARD, RH ;

PURVIS, JL .

ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS, 1973, 154 (01) :8-18

[9]

MUSTO N, 1972, ENDOCRINOLOGY, V91, P1106

[10]

NOVICK WJ, 1966, J PHARMACOL EXP THER, V151, P139

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