PYRUVATE CYCLE IN ADIPOSE TISSUE

被引：19

作者：

ROGNSTAD, R

机构：

[1] Cedars-Sinai Medical Research Institute, Cedars-Sinai Medical Center, Los Angeles

来源：

ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS | 1969年 / 129卷 / 01期

关键词：

D O I：

10.1016/0003-9861(69)90144-1

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

A model of adipose tissue metabolism was tested that involved an interaction of the Krebs cycle and the pyruvate cycle. The ratio of the specific yield in 14CO2 from succinate-1,4-14C to that from succinate-2,3-14C agreed well with the ratio predicted by the model. However, the ratio of the specific yield in 14CO2 from acetate-1-14C to that from acetate-2-14C was considerably lower than this ratio. Degradation of the lactate produced in incubations of adipose tissue slices with glucose-6-14C yielded a pattern that agreed with a model in which oxalacetate, malate, and fumarate were assumed to be nearly in isotopic equilibrium. © 1969.

引用

页码：13 / &

共 19 条

[1] INCORPORATION OF CITRATE CARBON INTO FATTY ACIDS [J].