DIAMINE-OXIDASE ACTIVITY AND TISSUE DIAMINE AND POLYAMINE CONTENTS OF HUMAN OVARIAN, CERVICAL AND ENDOMETRIAL CARCINOMA

被引：27

作者：

CHANDA, R ^{[1
]}

GANGULY, AK ^{[1
]}

机构：

[1] UNIV CALCUTTA,COLL MED,DEPT PHYSIOL,CALCUTTA 700020,W BENGAL,INDIA

来源：

CANCER LETTERS | 1995年 / 89卷 / 01期

关键词：

HISTAMINE; CADAVERINE; PUTRESCINE; SPERMINE; SPERMIDINE; DIAMINE-OXIDASE; OVARIAN CARCINOMA; CERVICAL CARCINOMA; ENDOMETRIAL CARCINOMA;

D O I：

10.1016/0304-3835(94)03648-3

中图分类号：

R73 [肿瘤学];

学科分类号：

100214 ;

摘要：

In view of the conflicting reports regarding the association of di- and poly-amines along with diamine oxidase (DAO) activity in human carcinomatous growths, the present study was undertaken to establish their interrelation and to justify whether analysis of di- and poly-amine contents along with DAO may have any diagnostic value in the assessment of the carcinomatous state. It was found that diamines like histamine, putrescine and cadaverine, and polyamines like spermine and spermidine, and also DAO, increased unequivocally in human ovarian, cervical and endometrial carcinoma in comparison with their adjoining normal tissues. A reasonable explanation has been put forward to support the observations made.

引用

页码：23 / 28

页数：6

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