RELATIONSHIP IN HUMANS BETWEEN ASCORBIC-ACID CONSUMPTION AND LEVELS OF TOTAL AND REDUCED ASCORBIC-ACID IN LENS, AQUEOUS-HUMOR, AND PLASMA

被引：82

作者：

TAYLOR, A ^{[1
]}

JACQUES, PF ^{[1
]}

NADLER, D ^{[1
]}

MORROW, F ^{[1
]}

SULSKY, SI ^{[1
]}

SHEPARD, D ^{[1
]}

机构：

[1] SEWICKLEY PA VALLEY HOSP, SEWICKLEY, PA USA

来源：

CURRENT EYE RESEARCH | 1991年 / 10卷 / 08期

关键词：

D O I：

10.3109/02713689109013869

中图分类号：

R77 [眼科学];

学科分类号：

100212 ;

摘要：

The relationships between plasma, aqueous humor and lens ascorbic acid levels are examined in 131 samples from 127 patients. Mean ascorbate intake for nonsupplemented individuals was 148 mg/day or over two times the recommended daily allowance. A subset of 44 patients participated in a trial to assess the impact Of vitamin C supplementation of 2 grams per day on aqueous and lens ascorbic acid levels. Such supplementation significantly increased both total and reduced ascorbic acid levels in Plasma and aqueous and total ascorbic acid in the lens. Correlation coefficients relating total and reduced ascorbic acid levels in the three tissues ranged from 0.42 to 0.19 (p < 0.05 for all correlation coefficients). Over 60% of the ascorbate was present in the reduced form in plasma and aqueous, and about 50% of the lens ascorbate was in the reduced form.

引用

页码：751 / 759

页数：9

共 28 条

[1] STATE OF SULFHYDRYL-GROUPS IN NORMAL AND CATARACTOUS HUMAN LENS PROTEINS .2. CORTICAL AND NUCLEAR REGIONS [J].