DISPARATE ANTIOXIDANT ENZYME-ACTIVITIES IN CULTURED HUMAN CUTANEOUS FIBROBLASTS, KERATINOCYTES, AND MELANOCYTES

被引：115

作者：

YOHN, JJ

NORRIS, DA

YRASTORZA, DG

BUNO, IJ

LEFF, JA

HAKE, SS

REPINE, JE

机构：

[1] UNIV COLORADO, SCH MED, DEPT MED, DENVER, CO 80202 USA

[2] UNIV COLORADO, SCH MED, WEBB WARING LUNG INST, DENVER, CO 80202 USA

[3] DEPT VET AFFAIRS MED CTR, DERMATOL SERV, DENVER, CO USA

来源：

JOURNAL OF INVESTIGATIVE DERMATOLOGY | 1991年 / 97卷 / 03期

关键词：

D O I：

10.1111/1523-1747.ep12480983

中图分类号：

R75 [皮肤病学与性病学];

学科分类号：

100206 ;

摘要：

Antioxidant enzyme activities of cultured human foreskin fibroblasts, keratinocytes, and melanocytes from healthy black and Caucasian donors were measured and compared. Fibroblasts had more (p < 0.05) peroxidase, catalase, glutathione peroxidase, and superoxide dismutase activity than keratinocytes. Keratinocytes had more (p < 0.05) peroxidase catalase, glutathione peroxidase, and superoxide dismutase activity than melanocytes. No differences in antioxidant enzyme activities were observed between the cells of any type taken from black or Caucasian people. Antioxidant enzyme activities may affect resistance to damage by oxidants induced by ultraviolet radiation and inflammation.

引用

页码：405 / 409

页数：5

共 40 条

[1] PARAMAGNETIC RESONANCE SPECTRA OF SOME SEMIQUINONE FREE RADICALS [J].