LANGERHANS CELL HISTIOCYTOSIS AND THE NERVOUS-SYSTEM

被引：21

作者：

BURN, DJ

WATSON, JDG

RODDIE, M

CHU, AC

LEGG, NJ

FRACKOWIAK, RSJ

机构：

[1] UCL NATL HOSP NEUROL & NEUROSURG, LONDON, ENGLAND

[2] HAMMERSMITH HOSP, DEPT MED, NEUROL UNIT, LONDON W12 0HS, ENGLAND

[3] HAMMERSMITH HOSP, DEPT DIAGNOST RADIOL, LONDON W12 0HS, ENGLAND

[4] HAMMERSMITH HOSP, DEPT MED, DERMATOL UNIT, LONDON W12 0HS, ENGLAND

来源：

JOURNAL OF NEUROLOGY | 1992年 / 239卷 / 06期

关键词：

LANGERHANS CELL HISTIOCYTOSIS; CENTRAL NERVOUS SYSTEM;

D O I：

10.1007/BF00867593

中图分类号：

R74 [神经病学与精神病学];

学科分类号：

摘要：

We report two cases of Langerhans' cell histiocytosis with unusual central nervous system (CNS) involvement. The first patient had behavioural disturbances, memory loss and diabetes insipidus. His response to a range of treatments was poor. The second patient presented with seizures and headaches suggestive of raised intracranial pressure. Etoposide (VP16) chemotherapy led to a dramatic clinical and radiologicaL improvement. The various CNS manifestations of Langerhans' cell histiocytosis and their management are discussed.

引用

页码：345 / 350

页数：6

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