IMMUNE HEMOLYSIS, DISSEMINATED INTRAVASCULAR COAGULATION, AND SERUM SICKNESS AFTER LARGE DOSES OF IMMUNE GLOBULIN GIVEN INTRAVENOUSLY FOR KAWASAKI-DISEASE

被引：62

作者：

COMENZO, RL

MALACHOWSKI, ME

MEISSNER, HC

FULTON, DR

BERKMAN, EM

机构：

[1] NEW ENGLAND MED CTR HOSP, DIV HEMATOL,DEPT MED,TRANSFUS MED SERV, 750 WASHINGTON ST, BOSTON, MA 02111 USA

[2] NEW ENGLAND MED CTR HOSP, DEPT MED, DIV HEMATOL ONCOL, BOSTON, MA 02111 USA

[3] NEW ENGLAND MED CTR HOSP, DEPT PATHOL, BOSTON, MA 02111 USA

[4] NEW ENGLAND MED CTR HOSP, TRANSFUS MED SERV, BOSTON, MA 02111 USA

[5] TUFTS UNIV, FLOATING HOSP, SCH MED, BOSTON, MA 02111 USA

[6] NEW ENGLAND MED CTR HOSP, DEPT PEDIAT, BOSTON, MA 02111 USA

[7] NEW ENGLAND MED CTR HOSP, DIV INFECT DIS, BOSTON, MA 02111 USA

[8] NEW ENGLAND MED CTR HOSP, DIV PEDIAT CARDIOL, BOSTON, MA 02111 USA

来源：

JOURNAL OF PEDIATRICS | 1992年 / 120卷 / 06期

关键词：

D O I：

10.1016/S0022-3476(05)81964-X

中图分类号：

R72 [儿科学];

学科分类号：

100202 ;

摘要：

One week after treatment with intravenously administered immune globulin and aspirin, a child with Kawasaki disease had persistent fever and an increase in coronary artery diameter to >3 mm. Two additional doses of immune globulin were given intravenously. Rapid hemolysis occurred, followed by disseminated intravascular coagulation and serum sickness. Clinicians should be aware that immune globulin preparations contain antibodies to blood-type antigens that may cause significant hemolysis and disseminated intravascular coagulation.

引用

页码：926 / 928

页数：3

共 12 条

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