FLOW VELOCITY QUANTIFICATION IN HUMAN CORONARY-ARTERIES WITH FAST, BREATH-HOLD MR-ANGIOGRAPHY

被引：102

作者：

EDELMAN, RR

MANNING, WJ

GERVINO, E

LI, W

机构：

[1] Departments of Radiology and Medicine, Charles A. Dana Research Institute and Harvard Thorndike Laboratory of Beth Israel Hospital and Harvard Medical School, Boston, Massachusetts, 02215

[2] Department of Cardiovascular Division, Charles A. Dana Research Institute and Harvard Thorndike Laboratory of Beth Israel Hospital and Harvard Medical School, Boston, Massachusetts, 02215

来源：

JMRI-JOURNAL OF MAGNETIC RESONANCE IMAGING | 1993年 / 3卷 / 05期

关键词：

CORONARY VESSELS; MR; PHASE IMAGING; PULSE SEQUENCES; VASCULAR STUDIES; VELOCITY STUDIES;

D O I：

10.1002/jmri.1880030503

中图分类号：

R8 [特种医学]; R445 [影像诊断学];

学科分类号：

1002 ; 100207 ; 1009 ;

摘要：

Measurement of coronary artery flow velocities has, until now, largely required the use of invasive technologies. The authors have implemented a breath-hold magnetic resonance (MR) angiography technique for depicting the coronary arteries and for quantifying flow velocities. The method was tested in flow phantoms and then applied to a series of subjects: 11 subjects were studied at rest, and four were studied before and during pharmacologic stress induced by intravenous adenosine. Flow velocities at rest in the midportion of the right coronary artery were 9.9 cm/sec +/- 3.5 (n = 12); in the proximal left anterior descending coronary artery, they were significantly higher, measuring 20.5 cm/sec +/- 5.2 (n = 6). With adenosine, flow velocities typically increased at least fourfold. The authors conclude that noninvasive measurement of coronary artery flow velocities is feasible with MR angiography; this method may prove useful for determining the physiologic significance of coronary artery stenosis.

引用

页码：699 / 703

页数：5

共 19 条

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