ESTERASE-7, A COMMON CONSTITUENT OF NUMEROUS MOUSE TISSUES

被引:25
作者
LIPPS, A
RONAI, A
VONDEIMLING, O
机构
[1] Department of Chemical Pathology, University of Freiburg i. Breisgau
来源
COMPARATIVE BIOCHEMISTRY AND PHYSIOLOGY B-BIOCHEMISTRY & MOLECULAR BIOLOGY | 1979年 / 62卷 / 03期
关键词
D O I
10.1016/0305-0491(79)90200-1
中图分类号
Q5 [生物化学]; Q7 [分子生物学];
学科分类号
071010 ; 081704 ;
摘要
1. 1. Electrophoretic and staining techniques for the relatively specific demonstration of esterase-7 in mouse tissues are described. Esterase-7 was found to be a common constituent of most mouse tissues. 2. 2. The electrophoretic polymorphisms determined by three alleles a, b and c were studied in nine mouse strains. 3. 3. The banding pattern of esterase-7 is being described and the isoelectric points of the allelic bands are being estimated. 4. 4. Recombination studies on a further 129 animals confirmed that the Es-7 locus is tightly linked to Es-2 and Es-11. 5. 5. Esterase-7 precipitates with antiesterase-2 from the rabbit. 6. 6. It differs from esterase-2 by its individual substrate preference and by its susceptibility to inhibition by acylating agents. © 1979.
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页码:201 / 206
页数:6
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