REARRANGEMENT OF BAND 10Q22 IN LEIOMYOMA AND LEIOMYOSARCOMA OF THE UTERUS

被引：20

作者：

KIECHLESCHWARZ, M

BERGER, CS

SURTI, U

SANDBERG, AA

机构：

[1] SW BIOMED RES INST,CTR CANC,6401 E THOMAS RD,SCOTTSDALE,AZ 85251

[2] MAGEE WOMENS HOSP,DEPT PATHOL,PITTSBURGH,PA 15213

来源：

CANCER GENETICS AND CYTOGENETICS | 1990年 / 47卷 / 01期

关键词：

D O I：

10.1016/0165-4608(90)90268-F

中图分类号：

R73 [肿瘤学];

学科分类号：

100214 ;

摘要：

Cytogenetic analysis of a uterine leiomyoma from a 56-year-old woman revealed an interstitial deletion of chromosome 10, del(10)(q22q24), as the only chromosomal abnormality. Band 10q22 was also rearranged in a previously reported leiomyosarcoma of the uterus showing a t(10;17)(q22.1;p13) as the only change. These findings provide an additional example in soft tissue tumors for involvement of the same chromosomal regions in benign and malignant proliferation of cells from the same lineage. © 1990.

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页码：95 / 100

页数：6

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