NOVEL ISOCOUMARIN DERIVATIVES FROM ACHLYS-TRIPHLLA (BERBERIDACEAE)

被引：20

作者：

MIZUNO, M

YOSHIDA, S

IINUMA, M

TANAKA, T

LANG, FA

GOTO, K

机构：

[1] OTSUKA PHARMACEUT FACTORY INC, NEW DRUG RES LABS, MUYA, NARUTO 772, JAPAN

[2] SO OREGON STATE COLL, DEPT BIOL, ASHLAND, OR 97520 USA

来源：

CHEMICAL & PHARMACEUTICAL BULLETIN | 1990年 / 38卷 / 07期

关键词：

8-dihydroxy-3-(4 T-hydroxyphenylethenyl)isocoumarin 6; 8-dihydroxy-3-(41-hydroxy-; dihydroxyphenyletheny1)isocoumarin Achlys triphylla Berberidaceae 7-geranyl-6; phenylethyl)isocoumarin 7-geranyl-6;

D O I：

10.1248/cpb.38.2075

中图分类号：

R914 [药物化学];

学科分类号：

100701 ;

摘要：

Three new phenolic compounds with a novel skeleton were isolated from the underground parts of Achlys triphylla (Berberidaceae). The structures were established by means of spectroscopic methods to be 7-geranyl-6,8-dihydroxy-3-(4f-hydroxyphenylethy1)isocoumarin ([formula omited]) for achlisocoumarin I, 7-geranyl-6,8-dihydroxy-3-(4T-hydroxyphenylethenyl)isocoumarin ([formula omited]) for achlisocoumarin II, and 6,8-dihydroxy-3-(3T,4T-dihydroxyphenylethenyl)isocoumarin ([formula omited]) for achlisocoumarin III, respectively. © 1990, The Pharmaceutical Society of Japan. All rights reserved.

引用

页码：2075 / 2077

页数：3