WNT GENES AND VERTEBRATE DEVELOPMENT

被引：160

作者：

PARR, BA

MCMAHON, AP

机构：

[1] The Biological Laboratories, Harvard University, Cambridge, MA 02138

来源：

CURRENT OPINION IN GENETICS & DEVELOPMENT | 1994年 / 4卷 / 04期

关键词：

D O I：

10.1016/0959-437X(94)90067-D

中图分类号：

Q2 [细胞生物学];

学科分类号：

071009 ; 090102 ;

摘要：

A variety of experimental approaches have underscored the critical role played by secreted polypeptide factors, such as those encoded by members of the Wnt gene family, in many aspects of vertebrate embryogenesis. Recent papers have revealed restricted patterns of Wnt gene expression that delineate important subdivisions within the early forebrain and spinal cord, demonstrated that Wnt gene products can regulate mesoderm formation and gastrulation, and investigated how Wnt protein signaling may affect cell adhesion.

引用

收藏

页码：523 / 528

页数：6

相关论文

共 57 条

[1] MIDLINE CELLS AND THE ORGANIZATION OF THE VERTEBRATE NEURAXIS [J].

ALTABA, ARI ;

JESSELL, TM .

CURRENT OPINION IN GENETICS & DEVELOPMENT, 1993, 3 (04) :633-640

[2] CONTROL OF CELL PATTERN IN THE NEURAL-TUBE - REGULATION OF CELL-DIFFERENTIATION BY DORSALIN-1, A NOVEL TGF-BETA FAMILY MEMBER [J].

BASLER, K ;

EDLUND, T ;

JESSELL, TM ;

YAMADA, T .

CELL, 1993, 73 (04) :687-702

[3] EXPRESSION OF WNT-1 IN PC12 CELLS RESULTS IN MODULATION OF PLAKOGLOBIN AND E-CADHERIN AND INCREASED CELLULAR ADHESION [J].

BRADLEY, RS ;

COWIN, P ;

BROWN, AMC .

JOURNAL OF CELL BIOLOGY, 1993, 123 (06) :1857-1865

[4]

BULFONE A, 1993, J NEUROSCI, V13, P3155

[5] XWNT-8 MODIFIES THE CHARACTER OF MESODERM INDUCED BY BFGF IN ISOLATED XENOPUS ECTODERM [J].

CHRISTIAN, JL ;

OLSON, DJ ;

MOON, RT .

EMBO JOURNAL, 1992, 11 (01) :33-41

[6]

CHRISTIAN JL, 1991, DEVELOPMENT, V111, P1045

[7] INTERACTIONS BETWEEN XWNT-8 AND SPEMANN ORGANIZER SIGNALING PATHWAYS GENERATE DORSOVENTRAL PATTERN IN THE EMBRYONIC MESODERM OF XENOPUS [J].

CHRISTIAN, JL ;

MOON, RT .

GENES & DEVELOPMENT, 1993, 7 (01) :13-28

[8] SPECIFICATION OF MESODERMAL PATTERN IN XENOPUS-LAEVIS BY INTERACTIONS BETWEEN BRACHYURY, NOGGIN AND XWNT-8 [J].

CUNLIFFE, V ;

SMITH, JC .

EMBO JOURNAL, 1994, 13 (02) :349-359

[9] THE ARMADILLO HOMOLOGS BETA-CATENIN AND PLAKOGLOBIN ARE DIFFERENTIALLY EXPRESSED DURING EARLY DEVELOPMENT OF XENOPUS-LAEVIS [J].

DEMARAIS, AA ;

MOON, RT .

DEVELOPMENTAL BIOLOGY, 1992, 153 (02) :337-346

[10] THE EFFECTS OF N-CADHERIN MISEXPRESSION ON MORPHOGENESIS IN XENOPUS EMBRYOS [J].

DETRICK, RJ ;

DICKEY, D ;

KINTNER, CR .

NEURON, 1990, 4 (04) :493-506

← 1 2 3 4 5 6 →