学术探索
学术期刊
新闻热点
数据分析
智能评审

IN VITRO SYNTHESIS OF 2'-OMETHYLGUANOSINE AND 2-METHYLTHIO [N (GAMMA, GAMMA, DIMETHYLALLYL) ADENOSINE IN TRANSFER RNA OF ESCHERICHIA COLI

被引：41
作者：
GEFTER, ML
机构：
[1] Medical Research Council, Laboratory of Molecular Biology, Cambridge, CB2 2QH England, Hills Road
来源：
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS | 1969年 / 36卷 / 03期
关键词：
2-methylthio, [!sup]6[!/sup]N (γ,γ, dimethylallyl) adenosine; 2-methylthio, [!sup]6[!/sup]N (γ,γ, dimethylallyl) adenosine 2′,3′ phosphate; 2-thio, [!sup]6[!/sup]N (γ,γ, dimethylallyl) adenosine; 2MSiPA; 2MSiPAp; 2SiPA; 30% triethylamine carbonate pH10; 5′ (2-omethyl) guanosylguanosine 2′; 3′; phosphate; !sup]6[!/sup]N (γ,γ, dimethylallyl) adenosine; dinucleoside diphosphates; GmG; iPA; mobility relative to 3′AMP; etc; R[!sub]3′AMP[!/sub; S-Adenosylmethionine; SAM; TEC; XY;
D O I：
10.1016/0006-291X(69)90583-X
中图分类号：
Q5 [生物化学]; Q7 [分子生物学];
学科分类号：
071010 ; 081704 ;
摘要：
A cell-free extract of E. coli catalyzes the transfer of the methyl group from S-adenosylmethionine1 to the 2′OH group of a guanosine residue present in a GG sequence in transfer RNAtyr. SAM is also shown to serve as a methyl donor in vitro for the synthesis of 2-methylthio 6N (γ,γ, dimethylallyl) adenosine in transfer RNA. © 1969.
引用
收藏
页码：435 / &
相关论文
共 11 条
12