SYNTHESIS OF THE INDIVIDUAL, PHARMACOLOGICALLY DISTINCT, ENANTIOMERS OF A TETRAHYDROCANNABINOL DERIVATIVE

被引：101

作者：

MECHOULAM, R

LANDER, N

BREUER, A

ZAHALKA, J

机构：

[1] Department of Natural Products, Hebrew University Medical Faculty, Jerusalem

来源：

TETRAHEDRON-ASYMMETRY | 1990年 / 1卷 / 05期

关键词：

D O I：

10.1016/S0957-4166(00)86322-3

中图分类号：

O61 [无机化学];

学科分类号：

070301 ; 081704 ;

摘要：

The individual enantiomers of the 1,1-dimethylheptyl homolog of 7-hydroxy- Δ6-tetrahydrocannabinol, (1) and (2a), which exhibit distinct pharmacological profiles, have beenobtained with very high e.e. by synthesis from the antipodes of myrtenol. © 1990.

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页码：315 / 318

页数：4

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