CHROMOSOME-ABERRATIONS IN AN ALPHA-FETOPROTEIN-PRODUCING HEPATOBLASTOMA

被引：20

作者：

ANNEREN, G

NORDLINDER, H

HEDBORG, F

机构：

[1] UNIV HOSP UPPSALA,DEPT PATHOL,S-75185 UPPSALA,SWEDEN

[2] UNIV HOSP UPPSALA,DEPT PAEDIAT,S-75185 UPPSALA,SWEDEN

来源：

GENES CHROMOSOMES & CANCER | 1992年 / 4卷 / 01期

关键词：

D O I：

10.1002/gcc.2870040117

中图分类号：

R73 [肿瘤学];

学科分类号：

100214 ;

摘要：

The cytogenetic findings of an alpha-fetoprotein (AFP)-producing hepatoblastoma in a 14-month-old girl are reported. Ten of 36 tumor cells were chromosomally abnormal, yielding the composite karyotype 47,XX,2q+,t(3;5)(p25;q31),dup(4)(q12q26), +20. Three of the chromosomal abnormalities (2q+, break at 4q12, +20) have been reported previously and might be of pathogenetic significance.

引用

页码：99 / 100

页数：2

共 7 条

[1]

BARDI G, 1991, CANCER GENET CYTOGEN, V51, P281

[2]

DOUGLASS EC, 1985, J NATL CANCER I, V75, P51

[3] CONSISTENT CYTOGENETIC ABERRATIONS IN HEPATOBLASTOMA - A COMMON PATHWAY OF GENETIC ALTERATIONS IN EMBRYONAL LIVER AND SKELETAL-MUSCLE MALIGNANCIES [J].