NITRIC-OXIDE - A PATHOGENETIC FACTOR IN AUTOIMMUNITY

被引：355

作者：

KOLB, H ^{[1
]}

KOLBBACHOFEN, V ^{[1
]}

机构：

[1] UNIV DUSSELDORF,DEPT IMMUNOBIOL,W-4000 DUSSELDORF 1,GERMANY

来源：

IMMUNOLOGY TODAY | 1992年 / 13卷 / 05期

关键词：

D O I：

10.1016/0167-5699(92)90118-Q

中图分类号：

R392 [医学免疫学]; Q939.91 [免疫学];

学科分类号：

100102 ;

摘要：

Nitric oxide (NO) has been identified recently as a multifunctional mediator, produced by, and acting on, most cells of the body. Besides its function as endothelium-derived relaxing factor, as a neurotransmitter and as an immune defence molecule, evidence is accumulating that NO participates in inflammatory- and autoimmune-mediated tissue destruction. Modulation of NO synthesis and action represents a new approach to the treatment of inflammatory and autoimmune conditions.

引用

页码：157 / 159

页数：3

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