POSITIVE AND NEGATIVE SYMPTOMS - RELATION TO FAMILIAL TRANSMISSION OF SCHIZOPHRENIA

被引：15

作者：

BARON, M ^{[1
]}

GRUEN, RS ^{[1
]}

ROMOGRUEN, JM ^{[1
]}

机构：

[1] COLUMBIA UNIV COLL PHYS & SURG,NEW YORK,NY 10032

来源：

BRITISH JOURNAL OF PSYCHIATRY | 1992年 / 161卷

关键词：

D O I：

10.1192/bjp.161.5.610

中图分类号：

R749 [精神病学];

学科分类号：

100205 ;

摘要：

The authors assessed the relevence of clinical symptoms to genetic research in schizophrenia in the nuclear families of 65 chronic schizophrenic probands. The morbidity risk for schizophrenia and schizotypal personality (a 'spectrum' disorder) was markedly reduced in first-degree relatives of probands with predominant negative symptoms, as compared with relatives of probands with other symptom patterns. The data support the notion that negative-symptom schizophrenia has an attenuated genetic component.

引用

页码：610 / 614

页数：5

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