SYNTHESIS OF OCTYL 2-O-ALPHA-D-MANNOPYRANOSYL-ALPHA-D-MANNOPYRANOSIDE, ITS 6'-PHOSPHATE AND THE CORRESPONDING MONOMETHYL PHOSPHODIESTER - INTERMEDIATE STRUCTURES IN THE BIOSYNTHESIS OF N-LINKED OLIGOSACCHARIDES IN DICTYOSTELIUM-DISCOIDIUM

被引:4
作者
HALLGREN, C [1 ]
HINDSGAUL, O [1 ]
机构
[1] UNIV ALBERTA,DEPT CHEM,EDMONTON T6G 2G2,AB,CANADA
关键词
D O I
10.1016/0008-6215(94)80022-7
中图分类号
Q5 [生物化学]; Q7 [分子生物学];
学科分类号
071010 ; 081704 ;
摘要
Octyl 2-O-alpha-D-mannopyranosyl-alpha-D-mannopyran its 6'-phosphate and the corresponding B-methyl phosphodiester have been chemically synthesized. The latter compound was prepared using an H-phosphonate intermediate. These structures are for use as enzyme substrates and reference standards in a study on the biosynthesis of phosphorylated N-linked glycoproteins in the amoebae Dictyostelium discoideum.
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页码:63 / 71
页数:9
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