SYNTHESIS OF OLIGOSACCHARIDE SUBSTRATES FOR N-LINKED GLYCOPROTEIN PROCESSING ENZYMES

被引：11

作者：

JAIN, RK ^{[1
]}

LIU, XG ^{[1
]}

ORUGANTI, SR ^{[1
]}

CHANDRASEKARAN, EV ^{[1
]}

MATTA, KL ^{[1
]}

机构：

[1] ROSWELL PK CANC INST,DEPT GYNECOL ONCOL,BUFFALO,NY 14263

来源：

CARBOHYDRATE RESEARCH | 1995年 / 271卷 / 02期

关键词：

OLIGOSACCHARIDE SUBSTRATES; N-LINKED GLYCOPROTEIN;

D O I：

10.1016/0008-6215(95)00073-3

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

The stereoselective syntheses of one pentasaccharide and one tetrasaccharide containing the Glc-alpha-(1 --> 3)-Man-alpha moiety as their terminal unit, as well as one tetrasaccharide and one trisaccharide containing the Man-alpha-(1 --> 2)-Man-alpha terminal unit were accomplished through the utilization of two key glycosyl donors, namely, 4-pentenyl 3-O-acetyl-2,4,6-tri-O-benzyl-alpha-D-mannopyranosideand ethyl 2-O-acetyl-3,4,6-tri-O-benzyl-1-thio-alpha-D-mannopyranoside.

引用

页码：185 / 196

页数：12

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