SYNTHESIS AND PHARMACOLOGY OF A SERIES OF 1-ARALKYL-3-BUTENYLAMINES

被引：15

作者：

MCCARTY, FJ

ROSENSTOCK, PD

PAOLINI, JP

MICUCCI, DD

ASHTON, L

BENNETTS, WW

PALOPOLI, FP

机构：

[1] National Drug Company, Research Laboratories, Division of Richardson-Merrell Inc., Philadelphia

来源：

JOURNAL OF MEDICINAL CHEMISTRY | 1968年 / 11卷 / 03期

关键词：

D O I：

10.1021/jm00309a028

中图分类号：

R914 [药物化学];

学科分类号：

100701 ;

摘要：

A series of substituted 1-benzyl-3-butenylamines related to aletamine was prepared and evaluated biologically for analgetic, anticonvulsant, antihypertensive, and antiinflammatory activity. A related series of 2-benzyl-4-pentylamines was also prepared and evaluated. © 1968, American Chemical Society. All rights reserved.

引用

页码：534 / +

页数：1

共 9 条

[1] THE CYCLISATION OF OLEFINIC ACIDS TO KETONES AND LACTONES
ANSELL, MF
PALMER, MH
[J]. QUARTERLY REVIEWS, 1964, 18 (02): : 211 - 225
[2] FELLOWS EJ, 1951, MEDICINAL CHEMISTRY, V1, P390
[3] GOLDSTEIN S, 1963, ARCH INT PHARMACOD T, V144, P269
[4] Grollman A, 1944, P SOC EXP BIOL MED, V57, P102
[5] HENDERSHOT LC, 1959, J PHARMACOL EXP THER, V125, P237
[6] MICUCCI DD, 1965, Patent No. 3210424
[7] SHEMANO I, IN PRESS
[8] SWINYARD EA, 1952, J PHARMACOL EXP THER, V106, P319
[9] 1967, 153 DIV MED CHEM NAT

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