NEUTRAL STEROID METABOLITES OF DEHYDROEPIANDROSTERONE-7ALPHA-3H IN HUMAN OVARIAN TISSUES

被引：4

作者：

FLICKINGER, GL

WU, CH

TOUCHSTONE, JC

机构：

[1] Department of Obstetrics, Gynecology University of Pennsylvania, Philadelphia

来源：

STEROIDS | 1968年 / 11卷 / 03期

关键词：

D O I：

10.1016/S0039-128X(68)80149-7

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

The metabolism of dehydroepiandrosterone-7α-3H by human ovarian tissues was studied by incubating slices of cortical stroma and corpora lutea of pregnancy. In the stroma the major metabolites of DHA were other androgens. A larger turnover of DHA occurred with luteal tissues and estrogens were the major metabolites. The isolation of Δ5-androstenediol, androstenedione and testosterone in all incubations suggests alternate pathways for the metabolism of DHA in both cortical stroma and corpora lutea. © 1968.

引用

页码：389 / +

页数：1

共 13 条

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