SYNAPTIC CURRENT AT SQUID GIANT SYNAPSE

被引:21
作者
GAGE, PW
MOORE, JW
机构
[1] School of Physiology, University of New South Wales, Kensington, NSW
[2] Department of Physiology and Pharmacology, Duke University, Durham
[3] Marine Biological Laboratory, Woods Hole
关键词
D O I
10.1126/science.166.3904.510
中图分类号
O [数理科学和化学]; P [天文学、地球科学]; Q [生物科学]; N [自然科学总论];
学科分类号
07 ; 0710 ; 09 ;
摘要
Transmission in the giant synapse of squid was studied by measuring synaptic currents in the voltage-clamped postsynaptic giant axon. These currents varied linearly with the axon's membrane potential, and showed an intercept on the voltage axis at, or near, the sodium equilibrium potential. The intercept shifted in seawater containing less sodium by even more than the shift in the sodium equilibrium potential. It is concluded that the transmitter at this synapse causes a significant change in the sodium conductance only.
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页码:510 / +
页数:1
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