PLASMA-EXCHANGE AND HEMOPERFUSION IN IODINE-INDUCED THYROTOXICOSIS

被引：6

作者：

PREUSCHOF, L

KELLER, F

BOGNER, U

REUTER, E

OFFERMANN, G

机构：

[1] Klinik für Radiologie und Nuklearmedizin, Freie Universität Berlin, Universitätsklinikum Steglilz

来源：

BLOOD PURIFICATION | 1991年 / 9卷 / 03期

关键词：

PLASMA EXCHANGE; HEMOPERFUSION; THYROTOXICOSIS; THYROXINE;

D O I：

10.1159/000170013

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

Iodine-induced thyrotoxicosis is a life-threatening disease. Plasma exchange and hemoperfusion are the available means of detoxication. Both methods were applied repeatedly to 4 patients with iodine-induced thyrotoxicosis, and the efficacy of these treatment methods was compared. Thyroxine plasma levels were decreased by 33%, while the calculated body stores were reduced by 18% during plasma exchange. Hemoperfusion was less effective. With both methods, a rebound of plasma levels was seen. Improvement of the clinical condition was delayed for 1 week after discontinuation of treatment. One patient died, probably because detoxication was discontinued too soon after the thyroid hormone levels had normalized. Plasma exchange by using albumin (120 g/4,000 ml = 30 g/1) as replacement fluid is superior to that by using fresh-frozen plasma (2,000 ml/4,000 ml), since less thyroxine is administered (19 vs. 160 nmol).

引用

页码：164 / 168

页数：5

共 8 条

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