INHIBITORS OF DE-NOVO FATTY-ACID BIOSYNTHESIS IN HIGHER-PLANTS

被引：22

作者：

GOLZ, A

FOCKE, M

LICHTENTHALER, HK

机构：

[1] Botanical Institute (Plant Physiology and Plant Biochemistry), University of Karlsruhe, Karlsruhe, D-76128

来源：

JOURNAL OF PLANT PHYSIOLOGY | 1994年 / 143卷 / 4-5期

关键词：

ACETYL-COA CARBOXYLASE; ACETYL-COA SYNTHETASE; ACETYLMETHYL PHOSPHINATE; ALKYL-ADENYLATES; CERULENIN; DIFLUFENICAN; FATTY ACID SYNTHETASE; GRAMINICIDES; INHIBITORS OF DE NOVO FATTY ACID BIOSYNTHESIS; THIOLACTOMYCIN;

D O I：

10.1016/S0176-1617(11)81802-X

中图分类号：

Q94 [植物学];

学科分类号：

071001 ;

摘要：

The present knowledge of de novo fatty acid biosynthesis in plastids of higher plants is reviewed with respect to its inhibition by various synthetic and natural xenobiotics. Certain enzymatic steps in the biosynthetic sequence, the acetyl-CoA synthetase (ACS), the acetyl-CoA carboxylase (ACC), the beta-ketoacyl-ACP synthases (KAS I and III) and the plastidic pyruvate dehydrogenase complex (pPDHC), are specifically inhibited by different synthetic compounds (ACS by alkyl-adenylates; ACC by herbicides, pPDHC by acetylmethyl-phosphinate) or by naturally occurring antibiotics (KAS enzymes by cerulenin and thiolactomycin). These xenobiotics can be used in a better understanding of the regulation of de novo fatty acid biosynthesis and the enzymes involved.

引用

页码：426 / 433

页数：8

共 68 条

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