METABOLISM OF ETHANOLAMINE PHOSPHOGLYCERIDES OF MOUSE BRAIN MYELIN AND MICROSOMES

被引:28
作者
HORROCKS, LA
机构
[1] Laboratory of Neurochemistry, Cleveland Psychiatric Institute, Cleveland, Ohio
关键词
D O I
10.1111/j.1471-4159.1969.tb10338.x
中图分类号
Q5 [生物化学]; Q7 [分子生物学];
学科分类号
071010 ; 081704 ;
摘要
Abstract— Three groups of six mice each were killed 1, 4 and 7 days after an intracerebral injection of [1,2‐14C]ethanolamine. The specific radioactivities of the acid‐labile ethanolamine phosphoglycerides (ethanolamine plasmalogens) and of the acid‐stable ethanolamine phosphoglycerides (diacyl and alkyl acyl glycerophosphoryletholamines) from myelin and microsomal fractions were determined. All of these brain ethanolamine phosphoglycerides turn over rapidly with an apparent half‐life of less than 3 days. The biosynthesis of alkenyl acyl glycerophosphorylethanolamines from diacyl glycerophosphorylethanolamines in mouse brain myelin or microsomes is unlikely. Copyright © 1969, Wiley Blackwell. All rights reserved
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页码:13 / &
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