A CASE OF MATERNITY TESTING - EXCLUSION BY POLYMORPHIC VNTR MARKERS OF DNA

被引：3

作者：

AKANE, A

NAKAJIMA, H

SHIONO, H

MATSUBARA, K

YAMADA, M

NAKAGOME, Y

机构：

[1] TOKYO MED & DENT UNIV,DEPT FORENS MED,BUNKYO KU,TOKYO 113,JAPAN

[2] NATL CHILDRENS MED RES CTR,DEPT CONGENITAL ABNORMALITIES RES,SETAGAYA KU,TOKYO 154,JAPAN

来源：

JAPANESE JOURNAL OF HUMAN GENETICS | 1990年 / 35卷 / 04期

关键词：

MATERNITY TESTING; DNA ANALYSIS; VNTR MARKERS;

D O I：

10.1007/BF01883754

中图分类号：

Q3 [遗传学];

学科分类号：

071007 ; 090102 ;

摘要：

The genetic markers of a Korean woman and her allegedly adopted child were compared to test her maternity. None of 21 conventional markers, including 8 red cell antigens, 6 red cell enzymes, and 7 serum proteins, excluded the maternity. These results indicate a maternal probability of 0.31 which was too low to conclude the true maternity. Human leukocyte antigen (HLA)-A, -B, -C and -DR haplotyping was also uniformative in this case. The maternity was consequently excluded by the observation of a difference in 2 of 5 variable number of tandem repeat (VNTR) markers.

引用

页码：319 / 323

页数：5

共 9 条

[1]

AKANE A, 1990, J FORENSIC SCI, V35, P1217

[2] SPONTANEOUS MUTATION-RATES TO NEW LENGTH ALLELES AT TANDEM-REPETITIVE HYPERVARIABLE LOCI IN HUMAN DNA [J].