CORRELATION BETWEEN THE INCREASE IN TYROSINE-HYDROXYLASE ACTIVITY AND THE DECREASE IN SEROTONIN CONTENT IN THE RAT LOCUS COERULEUS AFTER 5,6-DIHYDROXYTRYPTAMINE

被引：22

作者：

MCRAEDEGUEURCE, A

PUJOL, JF

机构：

[1] Département de Neurochimie Fonctionelle, INSERM U 171, Université Claude Bernard, 69373 Lyon, 8, Avenue Rockefeller

来源：

EUROPEAN JOURNAL OF PHARMACOLOGY | 1979年 / 59卷 / 1-2期

关键词：

5,6-Dihydroxytryptamine; Citalopram; Fluoxetine; Locus coeruleus; Serotonin; Tyrosine hydroxylase;

D O I：

10.1016/0014-2999(79)90035-9

中图分类号：

R9 [药学];

学科分类号：

1007 ;

摘要：

A correlation is demonstrated between the increase in tyrosine hydroxylase activity and the decrease in serotonin concentration in the rat locus coeruleus after various doses of 5,6-dihydroxytryptamine and gradual protection of serotonin neurons by pretreatment with two serotonin uptake inhibitors: fluoxetine or citalopram. © 1979.

引用

页码：131 / 135

页数：5

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