POLAROGRAPHY OF CEPHALOSPORIN C DERIVATIVES

被引：19

作者：

JONES, IF

PAGE, JE

RHODES, CT

机构：

[1] School of Pharmacy, Portsmouth College of Technology, Portsmouth, Hampshire

[2] Glaxo Research Limited, Greenford

来源：

JOURNAL OF PHARMACY AND PHARMACOLOGY | 1968年 / S 20卷

关键词：

D O I：

10.1111/j.2042-7158.1968.tb09860.x

中图分类号：

R9 [药学];

学科分类号：

1007 ;

摘要：

WE report some preliminary measurements on the polarographic reduction of cephalosporin C, cephalothin [7‐(2‐thienylacetamido)‐cephalosporanic acid] and cephaloridine [7‐(2‐thienylacetamido)‐3‐(1‐pyridylmethyl)‐3‐cephem‐4‐carboxylic acid betaine]. Green, Page & Staniforth (1965) have shown that cephalosporin C derivatives give well‐defined infrared and nuclear magnetic resonance spectra that can be used for their qualitative identification. Martin & Shaw (1965) have reviewed the application of methods such as ultraviolet spectrophotometry, paper chromatography and paper electrophoresis for cephaloridine, while Chapman, Page & others (1968) have described infrared and X‐ray powder measurements for this compound. The application of mass spectroscopy to the structural elucidation of cephalosporin derivatives has been reported by Richter & Biemann (1965). 1968 Royal Pharmaceutical Society of Great Britain

引用

页码：S45 / &

共 5 条

[1]

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PAGE, JE ;

PARKER, AC ;

ROGERS, D ;

SHARP, CJ ;

STANIFORTH, SE .

JOURNAL OF PHARMACY AND PHARMACOLOGY, 1968, 20 (06) :418-+

[3] CEPHALOSPORANIC ACIDS .I. INFRARED ABSORPTION AND PROTON MAGNETIC RESONANCE SPECTRA OF CEPHALOSPORIN AND PENICILLIN ANALOGUES [J].

GREEN, GFH ;

PAGE, JE ;

STANIFOR.SE .

JOURNAL OF THE CHEMICAL SOCIETY, 1965, (MAR) :1595-&

[4]

MARTIN JL, 1965, 1965 P SAC C NOTT, P32

[5] HOCHAUFLOSUNGS-MASSENSPEKTREN VON CEPHALOSPORIN-C-DERIVATEN [J].

RICHTER, W ;

BIEMANN, K .

MONATSHEFTE FUR CHEMIE UND VERWANDTE TEILE ANDERER WISSENSCHAFTEN, 1965, 96 (02) :484-&

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