MARROW GRAFTS BY COMBINED MARROW AND LEUKOCYTE INFUSIONS IN UNRELATED DOGS SELECTED BY HISTOCOMPATIBILITY TYPING

被引:141
作者
STORB, R
EPSTEIN, RB
BRYANT, J
RAGDE, H
THOMAS, ED
机构
[1] Department of Medicine, University of Washington School of Medicine, United States Public Health Service Hospital, Seattle, WA
关键词
D O I
10.1097/00007890-196807000-00011
中图分类号
R392 [医学免疫学]; Q939.91 [免疫学];
学科分类号
100102 ;
摘要
Consistent and rapid bone marrow grafts were produced in lethally irradiated dogs by infusions of marrow cells and peripheral blood leukocytes obtained from single living donors. Canine histocompatibility typing by lymphocyte cytotoxic antisera was evaluated in selecting donor-recipient pairs of unrelated dogs for marrow grafting. Significantly longer survival was observed in recipients that received marrow grafts from matched donors (IP > 0.01 < 0.02). © 1968 by The Williams and Wilkins Co.
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页码:587 / &
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