ISOLATION OF A CDNA CLONE, ENCODING A HUMAN BETA-GALACTOSIDE BINDING-PROTEIN, OVEREXPRESSED DURING GLUCOCORTICOID-INDUCED CELL-DEATH

被引：63

作者：

GOLDSTONE, SD

LAVIN, MF

机构：

[1] Queensland Cancer Fund Research Unit, Brisbane, 4006, Queensland Institute Medical Research Bramson Terrace, Herston

来源：

BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS | 1991年 / 178卷 / 02期

基金：

英国医学研究理事会;

关键词：

D O I：

10.1016/0006-291X(91)90171-3

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

In this report we describe the isolation and characterization of a cDNA clone overexpressed tenfold during the induction of apoptosis in the glucocorticoid-sensitive human leukaemia cell line CEM C7. This clone was shown by DNA sequence analysis to represent the human HL14 gene, encoding a β-galactoside binding protein, the mouse homologue of which has recently been reported to act as a cell growth inhibitory factor. © 1991.

引用

页码：746 / 750

页数：5

共 21 条

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