CHRONIC ANTIDEPRESSANT COUNTERACTS THE CONDITIONED ANALGESIA INDUCED BY A CONTEXT PREVIOUSLY ASSOCIATED WITH INESCAPABLE SHOCK

被引：7

作者：

MURUA, VS

MOLINA, VA

机构：

[1] NATL UNIV CORDOBA,FAC FILOSOFIA & HUMANIDADES,ESCUELA PSICOL,SUCURSAL 16,C-C 61,RA-5016 CORDOBA,ARGENTINA

[2] NATL UNIV CORDOBA,FAC CIENCIAS QUIM,DEPT FARMACOL,RA-5016 CORDOBA,ARGENTINA

来源：

PSYCHOPHARMACOLOGY | 1991年 / 105卷 / 03期

关键词：

INESCAPABLE SHOCK; CONDITIONED ANALGESIA; HOTPLATE TEST; CHRONIC ANTIDEPRESSANT DRUGS;

D O I：

10.1007/BF02244442

中图分类号：

Q189 [神经科学];

学科分类号：

071006 ;

摘要：

Rats exposed to a context previously paired with an inescapable shock session showed an increase in the paw lick and escape latencies in the hotplate test. This analgesic response was clearly reversed following chronic antidepressant drug administration. These findings indicate that chronic antidepressant treatment can influence the biological processes involved in the inescapable shock-induced conditioned analgesia

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页码：439 / 441

页数：3

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