THE OUTCOME OF PATIENTS WITH THYROID-CARCINOMA AND GRAVES-DISEASE

被引：41

作者：

KASUGA, Y

SUGENOYA, A

KOBAYASHI, S

MASUDA, H

IIDA, F

机构：

[1] The Department of Surgery, Shinshu University School of Medicine, Matsumoto, 390

来源：

SURGERY TODAY-THE JAPANESE JOURNAL OF SURGERY | 1993年 / 23卷 / 01期

关键词：

THYROID CARCINOMA; GRAVES DISEASE; THYROID STIMULATING ANTIBODY (TSAB);

D O I：

10.1007/BF00308993

中图分类号：

R61 [外科手术学];

学科分类号：

摘要：

A total 847 consecutive patients with Graves' disease who underwent thyroidectomy between 1965 and 1990 were found to have a 4.3% incidence of coincident carcinoma of the thyroid. In 68.2% of these cases the tumors were less than 1 cm in diameter and were detected in only 7 patients (19.4%) prior to surgery. Dissection of the regional lymph nodes was necessary in only 11 patients. A review of the patients in 1990 revealed no carcinoma-related deaths with metastases occurring most commonly in the patients with larger tumors and in those whose cancer had been detected prior to thyroidectomy. Although the detection of potential tumors occurring with Graves' disease using preoperative echogram may be of interest, our results suggest that occult micro-carcinoma occurring coincidentally with Graves' disease is not clinically significant as it did not cause any recurrence in this study. Moreover, there was no evidence to suggest that Graves' disease was associated with the increased or rapid growth of these tumors.

引用

页码：9 / 12

页数：4

共 13 条

[1]

Olen E., Klinck G.H., Hyperthyroidism and thyroid cancer, Arch Path, 81, pp. 531-535, (1966)

[2]

Shapiro S.J., Friedman N.B., Perzik S.L., Catz B., Incidence of thyroid carcinoma in Graves' disease, Cancer, 26, pp. 1261-1270, (1970)

[3]

Hancock B.W., Bing R.F., Dirmikis S.M., Munro D.S., Neal F.E., Thyroid carcinoma and concurrent hyperthyroidism, Cancer, 39, pp. 298-302, (1977)

[4]

Farbota L.M., Calandra D.B., Lawrence A.M., Poloyan E., Thyroid carcinoma in Graves' disease, Surgery, 98, pp. 1148-1153, (1985)

[5]

Behar R., Arganini M., Wu T.C., McCormick M., Straus F.H., DeGroot L.J., Kaplan E.L., Graves' disease and thyroid cancer, Surgery, 100, pp. 1121-1127, (1986)

[6]

Pacini F., Elisei R., Di Coscio G.C., Anelli S., Macchia E., Concetti R., Miccoli P., Arganini M., Pinchera A., Thyroid carcinoma in thyrotoxic patients treated by surgery, J Endocrinol Invest, 11, pp. 107-112, (1988)

[7]

Belfiore A., Garofalo, Giuffrida D., Runello F., Filetti S., Fiumara A., Ippolito O., Vigneri R., Increased aggressiveness of thyroid cancer in patients with Graves' disease, J Clin Endocrinol Metab, 70, pp. 830-835, (1990)

[8]

Makiuchi M., Miyakawa M., Sugenoya A., Furihata R., An evaluation of several prognostic factors in the surgical treatment for thyrotoxicosis, Surg Gynecol Obstet, 152, pp. 639-641, (1981)

[9]

Kasuga Y., Sugenoya A., Kobayashi S., Kaneko G., Masuda H., Fujimori M., Iida F., Clinical evaluation of the response to surgical treatment of Graves' disease, Surg Gynecol Obstet, 170, pp. 327-330, (1990)

[10]

Maruchi N., Furihata R., Makiuchi M., Population surveys on the prevalence of thyroid cancer in a non-endemic region, Nagano, Japan, Int J Cancer, 7, pp. 575-583, (1971)

← 1 2 →