POTENT NONPEPTIDE FIBRINOGEN RECEPTOR ANTAGONISTS WHICH PRESENT AN ALTERNATIVE PHARMACOPHORE

被引：31

作者：

KU, TW

MILLER, WH

BONDINELL, WE

ERHARD, KF

KEENAN, RM

NICHOLS, AJ

PEISHOFF, CE

SAMANEN, JM

WONG, AS

HUFFMAN, WF

机构：

[1] Research and Development Division, SmithKline Beecham Pharmaceuticals, King of Prussia, Pennsylvania 19406, 709 Swedeland Road

来源：

JOURNAL OF MEDICINAL CHEMISTRY | 1995年 / 38卷 / 01期

关键词：

D O I：

10.1021/jm00001a003

中图分类号：

R914 [药物化学];

学科分类号：

100701 ;

摘要：

[No abstract available]

引用

页码：9 / 12

页数：4

共 25 条

[1] CONFORMATIONALLY CONSTRAINED PEPTIDES AND SEMIPEPTIDES DERIVED FROM RGD AS POTENT INHIBITORS OF THE PLATELET FIBRINOGEN RECEPTOR AND PLATELET-AGGREGATION [J].

ALI, FE ;

BENNETT, DB ;

CALVO, RR ;

ELLIOTT, JD ;

HWANG, SM ;

KU, TW ;

LAGO, MA ;

NICHOLS, AJ ;

ROMOFF, TT ;

SHAH, DH ;

VASKO, JA ;

WONG, AS ;

YELLIN, TO ;

YUAN, CK ;

SAMANEN, JM .

JOURNAL OF MEDICINAL CHEMISTRY, 1994, 37 (06) :769-780

[2]

ALI FE, 1992, PEPTIDES CHEM BIOL, P761

[3] LOW-MOLECULAR-WEIGHT, NONPEPTIDE FIBRINOGEN RECEPTOR ANTAGONISTS [J].

ALIG, L ;

EDENHOFER, A ;

HADVARY, P ;

HURZELER, M ;

KNOPP, D ;

MULLER, M ;

STEINER, B ;

TRZECIAK, A ;

WELLER, T .

JOURNAL OF MEDICINAL CHEMISTRY, 1992, 35 (23) :4393-4407

[4] STRUCTURAL STUDIES OF A FAMILY OF HIGH-AFFINITY LIGANDS FOR GPIIB/IIIA [J].

BACH, AC ;

EYERMANN, CJ ;

GROSS, JD ;

BOWER, MJ ;

HARLOW, RL ;

WEBER, PC ;

DEGRADO, WF .

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 1994, 116 (08) :3207-3219

[5] CONFORMATIONAL-ANALYSIS OF CYCLIC HEXAPEPTIDES CONTAINING THE D-PRO-L-PRO SEQUENCE TO FIX BETA-TURN POSITIONS [J].

BEAN, JW ;

KOPPLE, KD ;

PEISHOFF, CE .

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 1992, 114 (13) :5328-5334

[6]

BONDINELL WE, 1993, Patent No. 95

[7]

BONDINELL WE, 1994, IN PRESS BIOORG MED, V2

[8]

BRISTOL JA, 1993, ANNU REP MED CHEM, V28, P79

[9]

GARTNER TK, 1985, J BIOL CHEM, V260, P1891

[10]

HANN MM, 1992, MOL RECOGNITION CHEM, V2, P145

← 1 2 3 →