BETA-ENDORPHIN CONCENTRATION IN THE BRAIN OF INTACT AND HYPOPHYSECTOMIZED RATS

被引：134

作者：

OGAWA, N

PANERAI, AE

LEE, S

FORSBACH, G

HAVLICEK, V

FRIESEN, HG

机构：

来源：

LIFE SCIENCES | 1979年 / 25卷 / 04期

关键词：

D O I：

10.1016/0024-3205(79)90261-3

中图分类号：

R-3 [医学研究方法]; R3 [基础医学];

学科分类号：

1001 ;

摘要：

The brain concentration and distribution of β-endorphin immunoreactivity in the brain have been studied in intact and hypophysectomized rats. The results obtained with different methods for killing the animals and extracting β-endorphin are compared. Different methodologies of killing the rat and extracting the brain yield concentrations of β-endorphin which vary ten fold. Consistently the highest concentrations of β-endorphin have been found in the hypothalamus, midbrain and hindbrain. After hypophysectomy major reduction of β-endorphin concentration in the brain was observed. © 1979.

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页码：317 / 325

页数：9

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