ONCE-DAILY ANTIBIOTIC REGIMEN IN PEDIATRIC ONCOLOGY

被引：20

作者：

BOUFFET, E

FUHRMANN, C

FRAPPAZ, D

COUILLIOUD, D

ARTIGES, V

CHARRA, C

BOUHOUR, D

MENTIGNY, MB

机构：

[1] Paediatric Department, Centre L Bérard, 69373, Lyon, Cedex 8

来源：

ARCHIVES OF DISEASE IN CHILDHOOD | 1994年 / 70卷 / 06期

关键词：

D O I：

10.1136/adc.70.6.484

中图分类号：

R72 [儿科学];

学科分类号：

100202 ;

摘要：

The feasibility and efficacy of a once daily antibiotic regimen were assessed Over a 44 month period, 296 febrile episodes were treated with a regimen of once daily ceftriaxone-amikacin (and teicoplanin or vancomycin if the patient had a central Line). The treatment was successful in 272 (92%) episodes without modification of the antibiotic regimen, and only one patient died of uncontrolled sepsis. A once daily antibiotic regimen is therefore feasible and worthwhile in the treatment of febrile episodes in children with cancer.

引用

页码：484 / 487

页数：4

共 21 条

[1]

BARRIERE SL, 1984, CLIN PHARMACY, V3, P351

[2]

CALANDRA T, 1987, NEW ENGL J MED, V317, P1692

[3] CLINICAL AND PHARMACOKINETIC STUDY OF A SINGLE DAILY DOSE OF AMIKACIN IN PEDIATRIC-PATIENTS WITH SEVERE GRAM-NEGATIVE INFECTIONS [J].